Chicken and Spinach Artichoke Casserole golden brown and bubbly

Casseroles

chicken and spinach artichoke casserole: comfort food reinvented

By:

Savory Touch

Published:

03 Aug 2025
Chicken and Spinach Artichoke Casserole golden brown and bubbly
I've always believed that the heart of any gathering lies in the food we share. There’s something incredibly comforting about a warm casserole, especially when it's loaded with delicious, wholesome ingredients. I remember one particularly chilly evening when my friends and I decided to throw together whatever we could find in the kitchen. The result? This Chicken and Spinach Artichoke Casserole! It was an instant hit, and it’s been a staple in my recipe collection ever since. It's also a great way to use up leftover chicken, which is always a plus in my book!
Overhead shot of the finished Chicken and Spinach Artichoke Casserole in a baking dish
This casserole isn't just about convenience; it’s about creating a dish that’s both satisfying and nutritious. The combination of chicken, spinach, and artichoke hearts provides a balanced meal packed with protein, vitamins, and fiber. Plus, it’s incredibly versatile! You can easily customize it with different cheeses, vegetables, or even add a touch of spice to kick things up a notch. One time, I added a pinch of red pepper flakes, and it gave it just the right amount of zing!
Close-up of a serving of Chicken and Spinach Artichoke Casserole on a plate
What I love most about this recipe is its ability to bring people together. Whether it’s a weeknight family dinner or a potluck with friends, this casserole is always a crowd-pleaser. It’s easy to make, requires minimal effort, and tastes absolutely divine. What more could you ask for? Ready to dive in? Let's get cooking!
Ingredients for Chicken and Spinach Artichoke Casserole laid out on a kitchen counter

Required Equipments

  • 9x13 inch baking dish
  • Large skillet
  • Mixing bowls
  • Whisk
  • Measuring cups and spoons

Chicken and Spinach Artichoke Casserole: Comfort Food Reinvented: Frequently Asked Questions

Chicken and Spinach Artichoke Casserole: Comfort Food Reinvented

This Chicken and Spinach Artichoke Casserole recipe combines tender chicken, nutrient-rich spinach, and flavorful artichoke hearts in a creamy, cheesy sauce. It's the perfect comfort food for any occasion, easy to make, and sure to be a family favorite!

⏳ Yield & Time

Yield: 6 servings

Preparation Time: 15 minutes

Cook Time: 25 minutes

Total Time:

🍽 Ingredients

📖 Instructions

  1. Preheat your oven to 375°F (190°C). Lightly grease a 9x13 inch baking dish with cooking spray. This keeps the casserole from sticking and makes cleanup a breeze.
  2. In a large skillet, melt 2 tablespoons of butter over medium heat. Add 1 diced onion and cook until softened, about 5 minutes. Nobody likes crunchy onions in their casserole, ya know?
  3. Add 2 cloves of minced garlic and cook for another minute, until fragrant. Watch it close so it doesn't burn!
  4. Stir in 1/4 cup of all-purpose flour and cook for 1 minute, creating a roux. This will help thicken the sauce and give it a creamy texture. Make sure to stir constantly to avoid lumps.
  5. Gradually whisk in 2 cups of chicken broth and 1 cup of heavy cream. Bring to a simmer, stirring constantly, until the sauce has thickened slightly, about 3-5 minutes. It should coat the back of a spoon.
  6. Remove the skillet from the heat. Stir in 10 ounces of frozen spinach (thawed and squeezed dry), 1 (14-ounce) can of artichoke hearts (drained and chopped), 1 cup of cooked, shredded chicken, 1/2 cup of grated Parmesan cheese, 1/4 cup of mayonnaise, and 1/4 teaspoon of salt and pepper, or too taste. Mix well until everything is evenly combined.
  7. Pour the mixture into the prepared baking dish, spreading it out evenly. Top with 1 cup of shredded mozzarella cheese.
  8. Bake for 20-25 minutes, or until the casserole is golden brown and bubbly. The cheese should be melted and slightly browned. Let it cool for a few minutes before serving. It's gonna be HOT!
  9. Serve warm and enjoy your delicious Chicken and Spinach Artichoke Casserole! Serve it with a side salad or some crusty bread for dipping. It's a crowd-pleaser, I promise you.

📝 Notes

    🍎 Nutrition

    Calories: 350 kcal

    Protein: 20g

    Fat: 25g

    Carbohydrates: 15g

    Fiber: 3g

    Calcium: 250mg

    The best meals are those that bring people together. This casserole is a hug on a plate. – Evelyn Reed

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